SUPER PEDIGREE ANALYSIS(This activity was taken from a workshop put on by Ball State University. It has been slightly modified for this website.) Assume the members of the above family are affected by genetic traits as described in each problem. For example, problem 1, describes a genetic trait that affects family members 1,3,5,11,13,19. You should have your students shade in their circle or square because they are the ones affected by this trait. The students should then use their knowledge about the patterns of inheritance each mode exhibits to determine which mode(s) of inheritance are possible for this particular trait. They can then support their hypothesis by assigning genotypes to the individuals in the pedigree. Students quickly learn to eliminate possibilities. For example, it can't be Y-linked if females are shaded. Once they narrow it down to 2-4 possibilities they start to analyze more closely. Treat each problem separately. Each mode of inheritance can be used in more than one problem. The problems may have more than one possible answer. The goal is for them to hypothesize on what is possible and support what they are saying. |
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Answers 1. ________ 2. ________ 3. ________ 4. ________ 5. ________ 6. ________ 7. ________ 8. ________ 9. ________ 10. _______ |
Affected Individuals 1, 3, 5, 11, 13, 19 1, 17, 18, 22 4, 10, 16, 17, 23 9, 16, 18 1, 3, 9, 11, 16, 17, 18 1, 2, 3, 7, 8, 9, 10, 16, 17, 23 1, 9, 17, 19 6, 7, 8, 23 2, 4, 5, 6, 7, 8, 10, 13, 14, 20 1, 9, 17, 18, 19 |
Types of Inheritance A. Y-linked B. Sex Limited C. Sex Influenced, Female Dominant D. Sex Influenced, Male Dominant E. X-linked Dominant F. X-linked Recessive G. Autosomal Dominant H. Autosomal Recessive |
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